Jersey Girl wrote:I have to ask a question here. Has anyone here heard of the process of growing stem cells from one's own blood supply?
I've heard of this in the news but I haven't read the primary research. What I understand is this: people who were in the early stages of type 1 Diabetes, and had not yet lost most/all of their insulin-producing cells, were treated with their own blood stem cells and showed great improvement.
Type 1 Diabetes is caused when a person's immune system attacks his own pancreas, destroying the ability to make insulin. The reason blood stem cells could heal this was function of the specific disease: white blood cells were the problem, and these cells could be wiped out and replaced by the patient's own healthy stem cells. However, it seems to me that the disease will likely recur since the person's own cells caused the immune reaction in the first place. Maybe this is just buying time or returning the patient to a state where a lifetime of immune-suppressing drugs can fend off the diabetes. Also, this worked for these patients because the disease was in an early stage.
Advanced type 1 diabetes, and other more common types of diabetes, could not be helped with blood stem cells because the insulin-producing cells of the pancreas would have to be replaced. I know of researchers in the US who would like to use embryonic stem cells to try and replace the function of a damaged pancreas. But they can't do this until the laws are changed.
asbestosman wrote:It reminds me of another question I also asked at MA&D. What are the limitations of researching other animal embrionic stem cells instead of human ones? Could we not use those to learn what we could and couldn't discover from human embrionic stem cells?
We have already seen some proof-of-principle studies in mice -- the most genetically manipulatable mammals. The limitation is that humans are different. We can't even clone human cells yet (and turn them into ES cells) -- this breakthrough is necessary to resolve the mysteries of several complex human diseases whether or not the ES cells are ultimately used in therapy. Once we have the answers, it will be easier to treat some diseases with adult stem cells or new drugs.
You might want to download this
essay by Dr. Kevin Eggan, who performed some of the proof-of-principle studies as a graduate student and is now trying to clone human ES cells with private money since the US government won't give him funds. The final section (Hope For The Future) is about using cloning technology to make ES cells for research instead of therapy.
Finally, it think it is of limited usefulness to explore this issue in terms of God vs. science because so many religious people -- especially Mormons -- do not believe that ES cell research is incompatible with a pro-life stance on abortion.