Vaccines and Therapeutics 2.0 & 3.0 Merge

[Jersey Girl]

Hot off the presses, folks. Here's the Pfizer vaccine study results from the New England Journal of Medicine.

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

https://www.nejm.org/doi/full/10.1056/N ... tured_home

[Doctor CamNC4Me]

Here is the esteemed Andrew Cuomo on the Covid vaccine before the election

[00:47:52]
I'm not that confident, but my opinion doesn't matter. I don't believe the American people are that confident. You're going to say to the American people, now, here's a vaccine. It was new. It was done quickly. But trust this federal administration in their health administration that it's safe and we're not one hundred percent sure of the consequences. I think it's going to be a very skeptical American public about taking the vaccine, and it should be they should be skeptical about the vaccine.

Here is Andrew Cuomo on the vaccine after the election

[00:48:43]
First we're going to have to have a real public education campaign to battle the skepticism. Just think of the math on this. You have to get the 75 percent to 85 percent of the overall population vaccinated for the vaccine to be effective, 75 to 85 percent, 50 percent of the population says right now they don't want to take the vaccine. They don't trust the approval process. They're worried about vaccines in general, but 50 percent are now saying they don't want to take the vaccine.

[00:49:15]
You cannot get to 75 percent if 50 percent don't take it.

https://www.happyscribe.com/public/the- ... 3e8b9d094b

I encourage you, 100%, to stick to your guns. I also encourage you to ensure all your closest associates who've been in your vaccine camp to also abide by their convictions and avoid the vaccine at all costs.

- Doc

[Doctor CamNC4Me]

Also, since Xanax is concerned with what personalities have to say about the vaccine, I'll repost this for his dumb ass since he didn't read it in the first place:

Trump has been saying the pandemic has been totally under control since January, and said it would just "go away" in February.

He reiterated this in March as the virus surged, and insisted we had "perfect" tests that anyone could get after reports of faulty tests. He said he wanted pandemic-related shutdowns to end by Easter so churches could be "packed" while claiming Hydroxychloroquine would be a miracle cure for COVID-19.

In April he continued to promote Hydroxychloroquine without evidence and suggested we could inject disinfectants or use UVC light inside the body to kill the virus, and right up through May Trump was discouraging the use of masks and refused to require them anywhere, with him and Pence famously flouting requirements at hospitals and factories. Trump also claimed he was taking Hydroxychloroquine as a prophylactic against the disease. At this point they were even planning to dismantle their own COVID-19 task force.

In June they were still insisting it was under control while fighting the FDA's revocation of authorizations for Hydroxychloroquine, and denying that there was a second surge happening. They instead blamed the high infection statistics on there being more testing, and Trump suggested slowing down testing to improve the stats, noting he does not joke.

Rolling into July he still insisted he had things under control, claiming they had done an incredible job, as the White House nuked a trove of data previously available through the CDC while Trump was still hyping Hydroxychloroquine and his son was temporarily suspended from Twitter for continuing to spread disinformation about it.

Even in August, Trump claimed COVID-19 was totally under control, and the ~150k dead with a simple "it is what it is,", and reiterated that the virus would go away all on its own. He finally encouraged the wearing of masks, but ignored all guidelines during his nomination acceptance speech at the Republican Convention.

In September Trump was saying that COVID-19 hurt "virtually nobody", and openly disputed the CDC's own claims about the effectiveness of masks.

In October Trump got COVID-19, and while still undergoing treatment, went on a quick spin around the hospital to wave to his supporters outside. He was discharged to the White House after only three days, posing for photo-ops without a mask. At this point White House officials finally concede that "we're not going to control the pandemic.". This would be the last time the COVID-19 task force would formally meet.

Since then Trump has pretty much avoided any and all public appearances except to complain about the election. November marked the point where a quarter of a million Americans had died of COVID-19. There are now more people dying each day of COVID-19 than died in the terrorist attacks on 9/11/2001 or in the Invasion of Normandy.

[Gadianton]

While Ajax tries to figure out what's right and wrong by believing whatever is opposite of what liberals say, I will remind everyone that while wearing a mask is primarily for the benefit of others (see Thomas Sowell on the logic of mud flaps), getting vaccinated for Covid protects you first. The effects of Covid are so variable and it's so relatively new, that combined with the fact that the vaccines are far more effective than flu vaccines, it's a no-brainer to get the Covid vaccine. The last I read (although this might have changed) is that it's less known how well the vaccine protects others. It prevents illness, but does it prevent the less-ill person from spreading?

Before I take it, I will undertake a cram session to be sure I haven't missed anything regarding known safety, as I also have concerns about the speed and newness --- but by the time it gets to me, I guess there will be a pretty solid body of data. I'm happy to take advantage of right-winger skepticism, I figure if Ajax and pals not taking it create an opportunity for me to get my chance earlier. Thanks guys!

[Res Ipsa]

The difference between the two Cuomo quotes is, of course, context. There was a time when Trump was attempting to impose his own ignorant opinions into the process of granting EUAs to therapeutics. The hydrochloriquine debacle is a good example, Cuomo was right to express concern about vaccine development being rushed for political reasons, with safety and efficacy taking a back seat.

The FDA then took steps to cut Trump’s politics out of vaccine development. It refused to accelerate the Pfizer approval even though Trump desperately wanted to be able to campaign on approval of a vaccine. It set up an independent review panel to evaluate Pfizer’s data and recommend whether to issue an EUA. In short, it took strong steps to show the approval would be based on the science, not politics. And the wisdom of that was shown by Trump yesterday, who threatened to fire the head of the FDA if the EUA wasn’t issued yesterday rather than today as planned. Why? News cycle, I’d guess.

Ajax just had to find someone to sneer at, when deep down I think he knows that the real problem is that his hero is an ignorant toddler who saw the entire pandemic through a single lens: what will get me re-elected?

[Res Ipsa]

While Ajax tries to figure out what's right and wrong by believing whatever is opposite of what liberals say, I will remind everyone that while wearing a mask is primarily for the benefit of others (see Thomas Sowell on the logic of mud flaps), getting vaccinated for Covid protects you first. The effects of Covid are so variable and it's so relatively new, that combined with the fact that the vaccines are far more effective than flu vaccines, it's a no-brainer to get the Covid vaccine. The last I read (although this might have changed) is that it's less known how well the vaccine protects others. It prevents illness, but does it prevent the less-ill person from spreading?

Before I take it, I will undertake a cram session to be sure I haven't missed anything regarding known safety, as I also have concerns about the speed and newness --- but by the time it gets to me, I guess there will be a pretty solid body of data. I'm happy to take advantage of right-winger skepticism, I figure if Ajax and pals not taking it create an opportunity for me to get my chance earlier. Thanks guys!

Dean Robbers, I have the same understanding you do. I have no concern over the safety of the vaccine or its effectiveness In protecting me. I am concerned that vaccinated folks will drop the other precautions, which could create unnecessary spread. And I’m guessing it will take until next Christmas to get everyone vaccinated who wants to be.

[Jersey Girl]

Here is the esteemed Andrew Cuomo on the Covid vaccine before the election

[00:47:52]
I'm not that confident, but my opinion doesn't matter. I don't believe the American people are that confident. You're going to say to the American people, now, here's a vaccine. It was new. It was done quickly. But trust this federal administration in their health administration that it's safe and we're not one hundred percent sure of the consequences. I think it's going to be a very skeptical American public about taking the vaccine, and it should be they should be skeptical about the vaccine.

Here is Andrew Cuomo on the vaccine after the election

[00:48:43]
First we're going to have to have a real public education campaign to battle the skepticism. Just think of the math on this. You have to get the 75 percent to 85 percent of the overall population vaccinated for the vaccine to be effective, 75 to 85 percent, 50 percent of the population says right now they don't want to take the vaccine. They don't trust the approval process. They're worried about vaccines in general, but 50 percent are now saying they don't want to take the vaccine.

[00:49:15]
You cannot get to 75 percent if 50 percent don't take it.

https://www.happyscribe.com/public/the- ... 3e8b9d094b

What about Trump's shifting positions?
What about one day it'll disappear, it'll be just like a miracle?
What about it's a hoax?
What about it's 5 times worse than the flu (to Woodward)?
What about (also to Woodward) I always wanted to down play it?
What about he wants to fire Fauci after the election?
What about he wants to now be basically recognized as the author of the Pfizer vaccine?
What about he threatened Stephen Hahn to force the FDA to approve the vaccine immediately?
What about the fact that there has been exactly NO public health education campaign by the Trump administration except...the one that is about to be launched 9 months too late and at the 11th hour as he leaves office?

What about the obvious fact that 50% of the population are afraid of the vaccine due to ALL of the above?

See? I can what about my butt off, too.

[Jersey Girl]

Ajax just had to find someone to sneer at, when deep down I think he knows that the real problem is that his hero is an ignorant toddler who saw the entire pandemic through a single lens: what will get me re-elected?

Bingo!

[Jersey Girl]

This from the NEJM concerns me a bit.

Four related serious adverse events were reported among BNT162b2 recipients (shoulder injury related to vaccine administration, right axillary lymphadenopathy, paroxysmal ventricular arrhythmia, and right leg paresthesia).

https://www.nejm.org/doi/full/10.1056/N ... tured_home

In fact, it wigged me out on first read. Having had a chance to think more about it while driving around in this iced over town earlier, here's my take speaking only for myself.

When I had AFIB I didn't just have AFIB. I had Paroxysmal AFIB with RVR which is rapid ventricular response. Something you don't want okay. You really, really, don't want that.

So...I am going to try to fish around more about this paroxysmal ventricular arrhythmia and see what's up with that. I didn't get to comb through the whole study yet. Maybe it was a one off, a one time event that was recorded. I'll figure that out. If it means dose me up and go get my heart shocked, no problem. I'm in it for protection against the virus and also in it for the propofol--which is from God.

[Doctor CamNC4Me]

Nooooo...

In his speech to fellow lawmakers upon being named speaker, he invoked a bipartisan tone.

"I ask each of you to not look at each other as Republicans and Democrats, but as friends and colleagues, working towards the same goal," Hinch said. "Our methods to get there and what we envision as a better New Hampshire may be different, but at the end of the day, please remember that we have a responsibility to respect each other and understand each other, that we are all here to make a positive difference in our communities and our state."

Also Dick Hinch:

In January 2019, just after the Democrats had taken control of the legislature, Hinch gave a rousing speech at the NHGOP state convention laying out policy issues he believed would work in his party's favor. As for Democrats, "I submit they are all bat-s*** crazy," Hinch said to cheers.

After googling for a bit I found Dick Hinch to be quote machine a la Trump.

Anyway. Back to Xanax. Xanax, it’s very, very important you let us Libs take this vaccine so we can get cancer, paralyzed, die in droves, etc. Like a fool, I want to get this vaccine asap, because I want to do some things in 2021 that require travel. Here’s your chance to stick it to me, by making way for us idiots who want this vaccine. Make way for us fools.

- Doc